AcelRx commences dosing in ARX-04 sufentanil NanoTab Phase 2 research for acute and breakthrough discomfort AcelRx Pharmaceuticals, Inc. , a specialty pharmaceutical company focused on the development and commercialization of innovative treatments for the treating acute and breakthrough pain, today announced that it has dosed the first subjects in a Phase 2, placebo-controlled, dose-finding research of its ARX-04 sufentanil NanoTab product applicant.S. Army Medical Materiel and Research Command, or USAMRMC.6 million grant to support the development of ARX-04, a proprietary non-invasive, fast-onset sublingual product candidate for the treating moderate-to-severe acute agony.Â.If you are on Twitter, you know that 50 Cent dropped from 214 to a scrawny 160 to seem sickly for his function in ‘Things Fall Apart. He regularly posted twitpics of himself getting thinner and thinner. And did you know Renee Zellweger gained almost 30 pounds to perform the title role in ‘Bridget Jones’s Diary.’ And then there’s Christian Bale, who lost 63 pounds to play the business lead in ‘The Machinist.’ See 10 many shocking celebrity weight changes.. Abdominal Exercises To Get Six Pack Abs Let’s face it. All of us want well-defined abs rather than the beer and pot bellies we find on other folks today but not all of us possess the period, the amount of money and the inclination to go to the gym on a normal basis.