The four programs studied for this record are My Choice My Long term in Powhatan County, Virginia; ReCapturing the Eyesight in Miami, Florida; Teenagers in Control in Clarksdale, Mississippi; and Families United to Prevent Teen Pregnancy in Milwaukee, Wisconsin. The first two programs serve middle schoolers; the latter two mainly serve elementary students – see system descriptions attached. These programs were chosen because these were well designed, stable, and offered services consistent with Name V, Section 510 guidelines, among other factors.The hormone performs a crucial role in rest and circadian rhythms, scavenging free radicals, antioxidant features, immunity, reproduction and mood regulation. Melatonin may combat viral and bacterial infections as well. Examples include chlamydial infections and Mycobacterium tuberculosis, amongst others. According to an assessment released in the journal Recent Patents on Endocrine, Metabolic & Immune Drug Discovery: ‘Melatonin’s protective action against sepsis is suggested to be because of its antioxidant, immunomodulating and inhibitory activities against the activation and creation of pro-inflammatory mediators. Use of melatonin has been beneficial in treating premature infants suffering from severe respiratory distress syndrome and septic shock.