Excision biopsy showed a markedly papillomatous epidermis included in a loose stratum corneum containing locules of blood. The skin was hyperplastic but lacked evident atypia. There was a prominent lymphocytic infiltrate hugging the epidermal junction at the dermal interface .. A bleeding lesion with a villous surface Seborrhoeic keratoses lose their characteristic dermatoscopic features often, and pale villous projections might be the only clue to the right diagnosis. Case presentation Over a six week period, a 64-year-old man noted an irritated lesion on his anterior chest . The lesion measured 8 mm in size and it bled. Dermoscopy exposed an increased lesion with multiple pale villous projections that were partially obscured by a dark eschar.All other adverse and severe adverse events were documented at each go to and had been graded on a scale that is useful for rating adverse occasions associated with vaccines, as suggested by the Division of Acquired Immunodeficiency Syndrome of the National Institute of Allergy and Infectious Illnesses assay in Thailand and the Procleix HIV discriminatory assay in the United States. We performed three measurements of HIV-1 RNA within 6 weeks after serodiagnosis to determine the mean postinfection viral load.