Plus its a combination of both internal and exterior misbalance that provides birth to acne on the skin. Precisely you can regard pimples as a hormonal disorder rather than a skin disease. Role of sebaceous gland There are essential oil glands present inside our skin that are known as sebaceous glands. These glands are activated with the hormonal secretion. When there is any imbalance in the creation of hormones, extra essential oil is produced by the skin by means of sebum. After the sebum starts getting clogged the follicle hair is dot-like and taken out spots come out. Initially they may be blackheads but steadily they take round or oval form and commonly become known as pimples and they are nothing but acne. Main hormone involved Which is the hormone that actually triggers this problem? The production of sebum in excess amount is certainly generated by androgens.John Ioannidis, chief of the Stanford Prevention Research Center, said in a university news release. Authors warn nevertheless that it would be hard to predict who is at higher risk for bone disease. People with the best number of variants associated with decreased bone mineral density were only about one. 5 times much more likely than people with an average quantity of variants to have osteoporosis. The risk for fractures was only slightly higher. Meanwhile, compared to people that have the fewest variants, people with the most variants had been still just three to four times more likely to have had fractures and lower bone mineral density, the study revealed. The authors noted, their research could lead to the advancement of new anti-osteoporosis medications.